Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

Abstract The cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes.Nevertheless, cryoEM sample preparation of Lounge Set challenging proteins and complexes, especially those with low abundance or with preferential orientation, remains a major hurdle.We developed an affini

read more

Cutaneous anthrax of the hand: Some clinical observations

CONTEXT: Anthrax is a very rare disease in Europe and the United States.AIM: A case of cutaneous anthrax of the hand with a wide skin defect is presented and some clinical observations highlighted.CASE REPORT: A 56-year-old male patient with cutaneous anthrax attended our infectious diseases department with a swelling up to the upper arm.An urgent

read more